Botulism
A rare illness caused by bacteria that make toxins in food
Overview
Botulism is a rare but serious illness caused by a toxin made by the bacteria Clostridium botulinum. The toxin affects how nerves and muscles work, which can make a person weak, unable to move, or have a hard time breathing
Alaska has one of the highest rates of botulism in the United States. The illness can occur when food is not aged, fermented, or preserved safely. Under these conditions, the bacteria can grow and produce toxin in the food.
To learn more about the different types of botulism, please visit the Centers for Disease Control and Prevention (CDC) page on botulism.
Public Health Emergency: Report Immediately
Public Health Emergency: Report Immediately
Providers and laboratories must report this condition immediately.
To report a Public Health Emergency
- Business Hours (8 a.m.-4:30 p.m.): 907-269-8000
- After Hours: 800-478-0084
For more information, visit Report a Health Condition
Symptoms & Diagnosis
Symptoms of botulism usually appear within 12-36 hours after eating food that contains the toxin, but they can also occur as early as six hours or as late as 10 days after exposure. The way symptoms show up, how quickly they appear, and how severe they are, depend on many factors like how much toxin has been eaten.
Symptoms may include:
- Difficulty swallowing
- Double vision
- Dry mouth
- Trouble talking or hoarse voice
- Blurred vision
- Drooping eyelids
- Facial paralysis
- Trouble Breathing or shortness of breath
- Constipation, diarrhea, or vomiting (in early illness)
Diagnosis is based on medical history and physical exams. Botulism can be confirmed by a lab test. However, treatment does not wait on test results, as they can take several weeks.
Treatment
Botulism is a medical emergency and requires medical care. Care may include medicine to stop the toxin and support for weak muscles, including help with breathing if needed. Early treatment can prevent symptoms from worsening and support recovery.
Without treatment, the illness can become life-threatening if breathing muscles are affected.
Prevention
The food safety tips below may reduce the risk of getting botulism when preparing preserved foods.
- Boil food for at least 10 minutes, or cook food at 176 degrees Fahrenheit or higher
- Do not count on freezing, as this will not destroy the poison
- Wash your hands, containers, and food
- Use salt to preserve dried fish
- Don’t use plastic buckets, glass containers, or sealed plastic bags to store or ferment foods.
- Do not eat canned foods that are bulging or sealed improperly.
- Age and store foods at a cold temperature, ideally below 37 degrees Fahrenheit
- Do not eat food if you do not know whether it was safely canned, preserved, or fermented
- When in doubt, throw it out! You cannot see, taste, or smell the toxin that causes botulism
For providers
Reporting
Reporting
Providers and laboratories must report this condition immediately.
To report a Public Health Emergency
- Business Hours (8 a.m.-4:30 p.m.): 907-269-8000
- After Hours: 800-478-0084
For more information, visit Report a Health Condition
Treatment
Treatment
Early intervention with Botulism Antitoxin (BAT) can stop progression of the toxin’s effects.
When botulism is suspected:
- You must consult with DOH Epidemiology immediately to determine if treatment with BAT is indicated.
- When treatment is indicated, Epidemiology will inform Alaska State Laboratories, so testing can proceed.
- Collect specimens for testing before treating with BAT.
Sample collection for lab testing
Sample collection for lab testing
Botulinum neurotoxin is detected in the laboratory in clinical specimens or suspect food samples. Alaska State Public Health Laboratories (ASPHL) will only test specimens from patients after ensuring they are being treated with the botulinum antitoxin (BAT). Specimens for Botulism testing include:
- Pre-antitoxin serum (10 mL minimum): It is critical that 20 mL of blood be drawn prior to the administration of BAT. The time the BAT is given is required on the Anchorage Lab Request form. Be certain the actual time of blood draw appears on the tubes and Anchorage Lab Request form.
- Stool (10 g minimum): Collect stool as soon as possible. Package without transport media. Ten grams is about the size of a walnut.
- Gastric Content (20 mL minimum): Collect gastric contents in a sterile, leak-proof container.
- Food (10 mL oil or 10 g of solid material minimum): Leave food in original containers if possible. Package in sterile, leak-proof containers.
Shipping samples for lab testing
Shipping samples for lab testing
Before shipping: Call ASPHL at 907-334-2100
All samples must be:
- Clearly labeled
- Placed in a leak-proof container
- Sealed with parafilm (please use duct tape for sealing oil samples)
- Placed in a sealable plastic bag with absorbent material
- Placed in second sealable plastic bag with completed Anchorage Lab Request form
- Packed as Biological Substance, Category B, according to IATA and DOT shipping regulations
- Shipped independently of other specimens for testing
Send Botulism samples to:
SPECIAL PATHOGENS
Alaska State Public Health Laboratories
5455 Dr. Martin Luther King Jr. Avenue
Anchorage, AK 99507
Botulism forms and documents
Botulism forms and documents
- BAT Admin Botulism Prescribing Information and Package insert
- Clinical Guidelines for Diagnosis and Treatment of Botulism
Botulism-related documents older than 25 months can be found on the State of Alaska Library Archives website.